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An In Situ Directing Group Strategy for Chiral Anion Phase-Transfer Fluorination of Allylic Alcohols

[Image: see text] An enantioselective fluorination of allylic alcohols under chiral anion phase-transfer conditions is reported. The in situ generation of a directing group proved crucial for achieving effective enantiocontrol. In the presence of such a directing group, a range of acyclic substrates...

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Detalles Bibliográficos
Autores principales: Zi, Weiwei, Wang, Yi-Ming, Toste, F. Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183625/
https://www.ncbi.nlm.nih.gov/pubmed/25203796
http://dx.doi.org/10.1021/ja507468u