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Molecular Basis for Self-Assembly of a Human Host-Defense Peptide That Entraps Bacterial Pathogens
[Image: see text] Human α-defensin 6 (HD6) is a 32-aa cysteine-rich peptide of the innate immune system. Although HD6 is a member of an antimicrobial peptide family, it exhibits negligible antibacterial activity in vitro. Rather, HD6 possesses a unique innate immune mechanism whereby it self-assembl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183631/ https://www.ncbi.nlm.nih.gov/pubmed/25158166 http://dx.doi.org/10.1021/ja5057906 |