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Facilitated Assignment of Large Protein NMR Signals with Covariance Sequential Spectra Using Spectral Derivatives

[Image: see text] Nuclear magnetic resonance (NMR) studies of larger proteins are hampered by difficulties in assigning NMR resonances. Human intervention is typically required to identify NMR signals in 3D spectra, and subsequent procedures depend on the accuracy of this so-called peak picking. We...

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Detalles Bibliográficos
Autores principales: Harden, Bradley J., Nichols, Scott R., Frueh, Dominique P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183633/
https://www.ncbi.nlm.nih.gov/pubmed/25226241
http://dx.doi.org/10.1021/ja5058407