A Phosphohistidine Proteomics Strategy Based on Elucidation of a Unique Gas-Phase Phosphopeptide Fragmentation Mechanism

[Image: see text] Protein histidine phosphorylation is increasingly recognized as a critical posttranslational modification (PTM) in central metabolism and cell signaling. Still, the detection of phosphohistidine (pHis) in the proteome has remained difficult due to the scarcity of tools to enrich an...

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Detalles Bibliográficos
Autores principales: Oslund, Rob C., Kee, Jung-Min, Couvillon, Anthony D., Bhatia, Vivek N., Perlman, David H., Muir, Tom W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183637/
https://www.ncbi.nlm.nih.gov/pubmed/25156620
http://dx.doi.org/10.1021/ja507614f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183637/
https://www.ncbi.nlm.nih.gov/pubmed/25156620
http://dx.doi.org/10.1021/ja507614f

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