Aminoluciferins Extend Firefly Luciferase Bioluminescence into the Near-Infrared and Can Be Preferred Substrates over d-Luciferin

[Image: see text] Firefly luciferase adenylates and oxidizes d-luciferin to chemically generate visible light and is widely used for biological assays and imaging. Here we show that both luciferase and luciferin can be reengineered to extend the scope of this light-emitting reaction. d-Luciferin can...

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Detalles Bibliográficos
Autores principales: Mofford, David M., Reddy, Gadarla Randheer, Miller, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183640/
https://www.ncbi.nlm.nih.gov/pubmed/25208457
http://dx.doi.org/10.1021/ja505795s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183640/
https://www.ncbi.nlm.nih.gov/pubmed/25208457
http://dx.doi.org/10.1021/ja505795s

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