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Aminoluciferins Extend Firefly Luciferase Bioluminescence into the Near-Infrared and Can Be Preferred Substrates over d-Luciferin
[Image: see text] Firefly luciferase adenylates and oxidizes d-luciferin to chemically generate visible light and is widely used for biological assays and imaging. Here we show that both luciferase and luciferin can be reengineered to extend the scope of this light-emitting reaction. d-Luciferin can...
Autores principales: | Mofford, David M., Reddy, Gadarla Randheer, Miller, Stephen C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183640/ https://www.ncbi.nlm.nih.gov/pubmed/25208457 http://dx.doi.org/10.1021/ja505795s |
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