De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters

[Image: see text] Enzyme-based tags attached to a protein-of-interest (POI) that react with a small molecule, rendering the conjugate fluorescent, are very useful for studying the POI in living cells. These tags are typically based on endogenous enzymes, so protein engineering is required to ensure...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Zhang, Xin, Tan, Yun Lei, Bhabha, Gira, Ekiert, Damian C., Kipnis, Yakov, Bjelic, Sinisa, Baker, David, Kelly, Jeffery W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183642/
https://www.ncbi.nlm.nih.gov/pubmed/25209927
http://dx.doi.org/10.1021/ja5056356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183642/
https://www.ncbi.nlm.nih.gov/pubmed/25209927
http://dx.doi.org/10.1021/ja5056356

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