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Human Serotonin Receptor 5-HT(1A) Preferentially Segregates to the Liquid Disordered Phase in Synthetic Lipid Bilayers

[Image: see text] We demonstrate successful incorporation of the G protein coupled receptor 5-HT(1A) into giant unilamellar vesicles using an agarose rehydration method. With direct observation using fluorescence techniques, we report preferential segregation of 5-HT(1A) into the cholesterol-poor li...

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Detalles Bibliográficos
Autores principales: Gutierrez, M. Gertrude, Malmstadt, Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183657/
https://www.ncbi.nlm.nih.gov/pubmed/25211019
http://dx.doi.org/10.1021/ja507221m