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Preparative Synthesis of Highly Substituted Tetrahydropyridines via a Rh(I)-Catalyzed C–H Functionalization Sequence

[Image: see text] We report a Rh(I)-catalyzed C–H activation/alkenylation/electrocyclization cascade and subsequent reduction for the synthesis of highly substituted tetrahydropyridines. These products can be accessed on a gram scale with low catalyst loadings and at high reaction concentrations. Ad...

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Detalles Bibliográficos
Autores principales: Mesganaw, Tehetena, Ellman, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183668/
https://www.ncbi.nlm.nih.gov/pubmed/25288872
http://dx.doi.org/10.1021/op500225c