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Epstein-Barr Virus Nuclear Antigen 3A Promotes Cellular Proliferation by Repression of the Cyclin-Dependent Kinase Inhibitor p21WAF1/CIP1

Latent infection by Epstein-Barr virus (EBV) is highly associated with the endemic form of Burkitt lymphoma (eBL), which typically limits expression of EBV proteins to EBNA-1 (Latency I). Interestingly, a subset of eBLs maintain a variant program of EBV latency - Wp-restricted latency (Wp-R) - that...

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Detalles Bibliográficos
Autores principales: Tursiella, Melissa L., Bowman, Emily R., Wanzeck, Keith C., Throm, Robert E., Liao, Jason, Zhu, Junjia, Sample, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183747/
https://www.ncbi.nlm.nih.gov/pubmed/25275486
http://dx.doi.org/10.1371/journal.ppat.1004415