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Ca(2+)-mediated Mitochondrial Reactive Oxygen Species Metabolism Augments Wnt/β-Catenin Pathway Activation to Facilitate Cell Differentiation

Emerging evidence suggests that reactive oxygen species (ROS) can stimulate the Wnt/β-catenin pathway in a number of cellular processes. However, potential sources of endogenous ROS have not been thoroughly explored. Here, we show that growth factor depletion in human neural progenitor cells induces...

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Detalles Bibliográficos
Autores principales: Rharass, Tareck, Lemcke, Heiko, Lantow, Margareta, Kuznetsov, Sergei A., Weiss, Dieter G., Panáková, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183826/
https://www.ncbi.nlm.nih.gov/pubmed/25124032
http://dx.doi.org/10.1074/jbc.M114.573519