Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway

BACKGROUND: Insulin-like growth factor binding protein-2 (IGFBP-2) is significantly increased in the serum of patients with malignant gliomas. High plasma IGFBP-2 levels are correlated with poor prognosis in glioma patients. However, the exact role of exogenous IGFBP-2 in gliomas is unclear. METHODS...

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Detalles Bibliográficos
Autores principales: Han, S, Li, Z, Master, L M, Master, Z W, Wu, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183856/
https://www.ncbi.nlm.nih.gov/pubmed/25093489
http://dx.doi.org/10.1038/bjc.2014.435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183856/
https://www.ncbi.nlm.nih.gov/pubmed/25093489
http://dx.doi.org/10.1038/bjc.2014.435

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