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SMAD1/5 Signaling in the Early Equine Placenta Regulates Trophoblast Differentiation and Chorionic Gonadotropin Secretion

TGFβ superfamily proteins, acting via SMAD (Sma- and Mad-related protein)2/3 pathways, regulate placental function; however, the role of SMAD1/5/8 pathway in the placenta is unknown. This study investigated the functional role of bone morphogenetic protein (BMP)4 signaling through SMAD1/5 in termina...

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Detalles Bibliográficos
Autores principales: Cabrera-Sharp, Victoria, Read, Jordan E., Richardson, Stephanie, Kowalski, Alycia A., Antczak, Douglas F., Cartwright, Judith E., Mukherjee, Abir, de Mestre, Amanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183921/
https://www.ncbi.nlm.nih.gov/pubmed/24848867
http://dx.doi.org/10.1210/en.2013-2116