An antibody reactive to the Gly(63)–Lys(68) epitope of NT-proBNP exhibits O-glycosylation-independent binding

The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP exhibits heavy O-linked glycosylation, and it is quite difficult to develop an antibod...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Yujean, Kim, Hyori, Chung, Junho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183943/
https://www.ncbi.nlm.nih.gov/pubmed/25236766
http://dx.doi.org/10.1038/emm.2014.57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183943/
https://www.ncbi.nlm.nih.gov/pubmed/25236766
http://dx.doi.org/10.1038/emm.2014.57

Ejemplares similares