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An antibody reactive to the Gly(63)–Lys(68) epitope of NT-proBNP exhibits O-glycosylation-independent binding
The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP exhibits heavy O-linked glycosylation, and it is quite difficult to develop an antibod...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183943/ https://www.ncbi.nlm.nih.gov/pubmed/25236766 http://dx.doi.org/10.1038/emm.2014.57 |