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Preeclampsia serum-induced collagen I expression and intracellular calcium levels in arterial smooth muscle cells are mediated by the PLC-γ1 pathway

In women with preeclampsia (PE), endothelial cell (EC) dysfunction can lead to altered secretion of paracrine factors that induce peripheral vasoconstriction and proteinuria. This study examined the hypothesis that PE sera may directly or indirectly, through human umbilical vein ECs (HUVECs), stimul...

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Detalles Bibliográficos
Autores principales: Jiang, Rongzhen, Teng, Yincheng, Huang, Yajuan, Gu, Jinghong, Ma, Li, Li, Ming, Zhou, Yuedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183944/
https://www.ncbi.nlm.nih.gov/pubmed/25257609
http://dx.doi.org/10.1038/emm.2014.59