The same self-peptide selects conventional and regulatory CD4(+) T cells with identical antigen receptors

The role of the T cell receptor (TCR) in commitment of thymocytes to regulatory CD4(+)Foxp3(+) and conventional CD4(−)Foxp3(−) T cell lineages remains controversial. According to the prevailing view, commitment to the former lineage, in contrast to the latter, requires that high affinity TCRs bind r...

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Detalles Bibliográficos
Autores principales: Wojciech, Lukasz, Ignatowicz, Alicja, Seweryn, Michal, Rempala, Grzegorz, Pabla, Simarjot Singh, McIndoe, Richard A., Kisielow, Pawel, Ignatowicz, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183978/
https://www.ncbi.nlm.nih.gov/pubmed/25270305
http://dx.doi.org/10.1038/ncomms6061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183978/
https://www.ncbi.nlm.nih.gov/pubmed/25270305
http://dx.doi.org/10.1038/ncomms6061

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