Cargando…
The same self-peptide selects conventional and regulatory CD4(+) T cells with identical antigen receptors
The role of the T cell receptor (TCR) in commitment of thymocytes to regulatory CD4(+)Foxp3(+) and conventional CD4(−)Foxp3(−) T cell lineages remains controversial. According to the prevailing view, commitment to the former lineage, in contrast to the latter, requires that high affinity TCRs bind r...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183978/ https://www.ncbi.nlm.nih.gov/pubmed/25270305 http://dx.doi.org/10.1038/ncomms6061 |