Base-cleavable microarrays for the characterization of DNA and RNA oligonucleotides synthesized in situ by photolithography

Assessing synthesis efficiency, errors, failed deprotections, and chemical and enzymatic degradation of oligonucleotides on microarrays is essential for improving existing in situ synthesis methods, and for the development of new chemistries. We describe the use of LC-MS to analyse DNA and RNA oligo...

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Detalles Bibliográficos
Autores principales: Lietard, Jory, Kretschy, Nicole, Sack, Matej, Wahba, Alexander S., Somoza, Mark M., Damha, Masad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183992/
https://www.ncbi.nlm.nih.gov/pubmed/25213224
http://dx.doi.org/10.1039/c4cc05771f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183992/
https://www.ncbi.nlm.nih.gov/pubmed/25213224
http://dx.doi.org/10.1039/c4cc05771f

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