An Unexpected Deamination Reaction after Hydrolysis of the Pyrimidine (6-4) Pyrimidone Photoproduct

[Image: see text] Pyrimidine (6-4) pyrimidone photoproduct (6-4PP), a common DNA photolesion formed under solar irradiation, was indicated to hydrolyze under strong basic conditions, breaking the N3–C4 bond at the 5′-thymine. The reanalysis of this reaction revealed that the resulting water adduct m...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Gengjie, Jian, Yajun, Ouyang, Hao, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184442/
https://www.ncbi.nlm.nih.gov/pubmed/25250878
http://dx.doi.org/10.1021/ol502433h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184442/
https://www.ncbi.nlm.nih.gov/pubmed/25250878
http://dx.doi.org/10.1021/ol502433h

Ejemplares similares