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Evaluation of Proteomic Search Engines for the Analysis of Histone Modifications

[Image: see text] Identification of histone post-translational modifications (PTMs) is challenging for proteomics search engines. Including many histone PTMs in one search increases the number of candidate peptides dramatically, leading to low search speed and fewer identified spectra. To evaluate d...

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Detalles Bibliográficos
Autores principales: Yuan, Zuo-Fei, Lin, Shu, Molden, Rosalynn C., Garcia, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184451/
https://www.ncbi.nlm.nih.gov/pubmed/25167464
http://dx.doi.org/10.1021/pr5008015