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Total Synthesis of Alkaloid 205B

[Image: see text] Concise and highly stereocontrolled total syntheses of racemic and enantiopure frog alkaloid 205B (1) were accomplished in 11 steps from 4-methoxypyridines 6 and 7 in overall yields of 8 and 8%, respectively. The assembly of the core of the natural product relies on a stereoselecti...

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Detalles Bibliográficos
Autores principales: Tsukanov, Sergey V., Comins, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184464/
https://www.ncbi.nlm.nih.gov/pubmed/25180567
http://dx.doi.org/10.1021/jo501415r