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Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid

OBJECTIVE: Brain amyloidosis is a key feature of Alzheimer's disease (AD). It also incorporates cerebrovascular amyloid β (Aβ) in the form of cerebral amyloid angiopathy (CAA) involving neurovascular dysfunction. We have recently shown by retrospective analysis that patients with mild cognitive...

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Detalles Bibliográficos
Autores principales: Maki, Takakuni, Okamoto, Yoko, Carare, Roxana O, Hase, Yoshiki, Hattori, Yorito, Hawkes, Cheryl A, Saito, Satoshi, Yamamoto, Yumi, Terasaki, Yasukazu, Ishibashi-Ueda, Hatsue, Taguchi, Akihiko, Takahashi, Ryosuke, Miyakawa, Taihei, Kalaria, Raj N, Lo, Eng H, Arai, Ken, Ihara, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184555/
https://www.ncbi.nlm.nih.gov/pubmed/25356424
http://dx.doi.org/10.1002/acn3.79