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Green fluorescent protein fused to peptide agonists of two dissimilar G protein-coupled receptors: novel ligands of the bradykinin B(2) (rhodopsin family) receptor and parathyroid hormone PTH(1) (secretin family) receptor

We hypothesized that peptide hormone sequences that stimulate and internalize G protein-coupled receptors (GPCRs) could be prolonged with a functional protein cargo. To verify this, we have selected two widely different pairs of peptide hormones and GPCRs that nevertheless share agonist-induced arre...

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Detalles Bibliográficos
Autores principales: Charest-Morin, Xavier, Fortin, Jean-Philippe, Bawolak, Marie-Thérèse, Lodge, Robert, Marceau, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184569/
https://www.ncbi.nlm.nih.gov/pubmed/25505558
http://dx.doi.org/10.1002/prp2.4