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Cilostazol prevents retinal ischemic damage partly via inhibition of tumor necrosis factor-α-induced nuclear factor-kappa B/activator protein-1 signaling pathway

Cilostazol is a specific inhibitor of phosphodiesterase III and is widely used to treat ischemic symptoms of peripheral vascular disease. We evaluated the protective effects of cilostazol in a murine model of ocular ischemic syndrome in which retinal ischemia was induced by 5-h unilateral ligation o...

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Detalles Bibliográficos
Autores principales: Ishizuka, Fumiya, Shimazawa, Masamitsu, Egashira, Yusuke, Ogishima, Hiromi, Nakamura, Shinsuke, Tsuruma, Kazuhiro, Hara, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184571/
https://www.ncbi.nlm.nih.gov/pubmed/25505560
http://dx.doi.org/10.1002/prp2.6