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Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo

N-methyl-d-aspartate receptor (NMDAR) activation can initiate changes in synaptic strength, evident as long-term potentiation (LTP), and is a key molecular correlate of memory formation. Inhibition of d-amino acid oxidase (DAAO) may increase NMDAR activity by regulating d-serine concentrations, but...

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Detalles Bibliográficos
Autores principales: Hopkins, Seth C, Campbell, Una C, Heffernan, Michele L R, Spear, Kerry L, Jeggo, Ross D, Spanswick, David C, Varney, Mark A, Large, Thomas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184572/
https://www.ncbi.nlm.nih.gov/pubmed/25505561
http://dx.doi.org/10.1002/prp2.7