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Selective antinociceptive effects of a combination of the N-methyl-D-aspartate receptor peptide antagonist [Ser(1)]histogranin and morphine in rat models of pain
Numerous rather than a few analgesic endogenous neuropeptides are likely to work in concert in vivo in ameliorating pain. Identification of effective neuropeptide combinations would also facilitate the development of gene or cell-based analgesics. In this study, opioid peptides endomorphin-1 (EM-1)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BlackWell Publishing Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184704/ https://www.ncbi.nlm.nih.gov/pubmed/25505581 http://dx.doi.org/10.1002/prp2.32 |