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Intestinal absorption of the antiepileptic drug substance vigabatrin is altered by infant formula in vitro and in vivo.

Vigabatrin is an antiepileptic drug substance mainly used in pediatric treatment of infantile spasms. The main source of nutrition for infants is breast milk and/or infant formula. Our hypothesis was that infant formula may affect the intestinal absorption of vigabatrin. The aim was therefore to inv...

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Detalles Bibliográficos
Autores principales: Nøhr, Martha Kampp, Thale, Zia I, Brodin, Birger, Hansen, Steen H, Holm, René, Nielsen, Carsten Uhd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184708/
https://www.ncbi.nlm.nih.gov/pubmed/25505585
http://dx.doi.org/10.1002/prp2.36