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Intestinal absorption of the antiepileptic drug substance vigabatrin is altered by infant formula in vitro and in vivo.
Vigabatrin is an antiepileptic drug substance mainly used in pediatric treatment of infantile spasms. The main source of nutrition for infants is breast milk and/or infant formula. Our hypothesis was that infant formula may affect the intestinal absorption of vigabatrin. The aim was therefore to inv...
Autores principales: | Nøhr, Martha Kampp, Thale, Zia I, Brodin, Birger, Hansen, Steen H, Holm, René, Nielsen, Carsten Uhd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184708/ https://www.ncbi.nlm.nih.gov/pubmed/25505585 http://dx.doi.org/10.1002/prp2.36 |
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