Orthovanadate-induced vasocontraction is mediated by the activation of Rho-kinase through Src-dependent transactivation of epidermal growth factor receptor

Orthovanadate (OVA), a protein tyrosine phosphatase (PTPase) inhibitor, exerts contractile effects on smooth muscle in a Rho-kinase-dependent manner, but the precise mechanisms are not elucidated. The aim of this study was to determine the potential roles of Src and epidermal growth factor receptor...

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Detalles Bibliográficos
Autores principales: Yayama, Katsutoshi, Sasahara, Tomoya, Ohba, Hisaaki, Funasaka, Ayaka, Okamoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184709/
https://www.ncbi.nlm.nih.gov/pubmed/25505586
http://dx.doi.org/10.1002/prp2.39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184709/
https://www.ncbi.nlm.nih.gov/pubmed/25505586
http://dx.doi.org/10.1002/prp2.39

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