The Gene Expression Response of Chronic Lymphocytic Leukemia Cells to IL-4 Is Specific, Depends on ZAP-70 Status and Is Differentially Affected by an NFκB Inhibitor

Interleukin 4 (IL-4), an essential mediator of B cell development, plays a role in survival of chronic lymphocytic leukemia (CLL) cells. To obtain new insights into the function of the IL-4 pathway in CLL, we analyzed the gene expression response to IL-4 in CLL and in normal B cells (NBC) by oligonu...

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Detalles Bibliográficos
Autores principales: Ruiz-Lafuente, Natalia, Alcaraz-García, María-José, Sebastián-Ruiz, Silvia, Gómez-Espuch, Joaquín, Funes, Consuelo, Moraleda, José-María, García-Garay, María-Carmen, Montes-Barqueros, Natividad, Minguela, Alfredo, Álvarez-López, María-Rocío, Parrado, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184842/
https://www.ncbi.nlm.nih.gov/pubmed/25280001
http://dx.doi.org/10.1371/journal.pone.0109533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184842/
https://www.ncbi.nlm.nih.gov/pubmed/25280001
http://dx.doi.org/10.1371/journal.pone.0109533

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