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Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a chronic, idiopathic cholangiopathy. The role of biliary epithelial cells, i.e. cholangiocytes, in PSC pathogenesis is unknown and remains an active area of research. Here, through cellular, molecular, and next-generation sequencing (NGS) methods, we characte...

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Detalles Bibliográficos
Autores principales: Tabibian, James H., Trussoni, Christy E., O’Hara, Steven P., Splinter, Patrick L., Heimbach, Julie K., LaRusso, Nicholas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184949/
https://www.ncbi.nlm.nih.gov/pubmed/25046437
http://dx.doi.org/10.1038/labinvest.2014.94