Non-cell autonomous tumor-growth driving supports sub-clonal heterogeneity

Cancers arise through a process of somatic evolution that can result in substantial sub-clonal heterogeneity within tumors. The mechanisms responsible for the coexistence of distinct sub-clones and the biological consequences of this coexistence remain poorly understood. Here we used a mouse xenogra...

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Detalles Bibliográficos
Autores principales: Marusyk, Andriy, Tabassum, Doris P., Altrock, Philipp M., Almendro, Vanessa, Michor, Franziska, Polyak, Kornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184961/
https://www.ncbi.nlm.nih.gov/pubmed/25079331
http://dx.doi.org/10.1038/nature13556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184961/
https://www.ncbi.nlm.nih.gov/pubmed/25079331
http://dx.doi.org/10.1038/nature13556

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