Using familial information for variant filtering in high-throughput sequencing studies

High-throughput sequencing studies (HTS) have been highly successful in identifying the genetic causes of human disease, particularly those following Mendelian inheritance. Many HTS studies to date have been performed without utilizing available family relationships between samples. Here, we discuss...

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Detalles Bibliográficos
Autores principales: Bahlo, Melanie, Tankard, Rick, Lukic, Vesna, Oliver, Karen L., Smith, Katherine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185103/
https://www.ncbi.nlm.nih.gov/pubmed/25129038
http://dx.doi.org/10.1007/s00439-014-1479-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185103/
https://www.ncbi.nlm.nih.gov/pubmed/25129038
http://dx.doi.org/10.1007/s00439-014-1479-4

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