Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children

Six rare functional coding mutations were previously identified in melanocortin 4 receptor (MC4R) in 6,760 American Indians. Individuals heterozygous for one of these mutations become obese while young. We now investigate whether common non-coding variation near MC4R also contributes to obesity. Fif...

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Detalles Bibliográficos
Autores principales: Muller, Yunhua L., Thearle, Marie S., Piaggi, Paolo, Hanson, Robert L., Hoffman, Duncan, Gene, Brittany, Mahkee, Darin, Huang, Ke, Kobes, Sayuko, Votruba, Susanne, Knowler, William C., Bogardus, Clifton, Baier, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185108/
https://www.ncbi.nlm.nih.gov/pubmed/25103139
http://dx.doi.org/10.1007/s00439-014-1477-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185108/
https://www.ncbi.nlm.nih.gov/pubmed/25103139
http://dx.doi.org/10.1007/s00439-014-1477-6

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