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Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node

The sinoatrial node (SAN) is essential for rhythmic beating of the heart; however, our understanding of what controls proper functioning of the SAN remains primitive. To explore molecular control of SAN function, we specifically deleted Baf250a, a key regulatory component of the ATP-dependent chroma...

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Detalles Bibliográficos
Autores principales: Wu, Meng, Peng, Siwu, Yang, Jialiang, Tu, Zhidong, Cai, Xiaoqiang, Cai, Chen-Leng, Wang, Zhong, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185344/
https://www.ncbi.nlm.nih.gov/pubmed/25145359
http://dx.doi.org/10.1038/cr.2014.113