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Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node
The sinoatrial node (SAN) is essential for rhythmic beating of the heart; however, our understanding of what controls proper functioning of the SAN remains primitive. To explore molecular control of SAN function, we specifically deleted Baf250a, a key regulatory component of the ATP-dependent chroma...
Autores principales: | Wu, Meng, Peng, Siwu, Yang, Jialiang, Tu, Zhidong, Cai, Xiaoqiang, Cai, Chen-Leng, Wang, Zhong, Zhao, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185344/ https://www.ncbi.nlm.nih.gov/pubmed/25145359 http://dx.doi.org/10.1038/cr.2014.113 |
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