Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity

Mediator complex is a molecular hub integrating signaling, transcription factors, and RNA polymerase II (RNAPII) machinery. Mediator MED23 is involved in adipogenesis and smooth muscle cell differentiation, suggesting its role in energy homeostasis. Here, through the generation and analysis of a liv...

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Detalles Bibliográficos
Autores principales: Chu, Yajing, Rosso, Leonardo Gómez, Huang, Ping, Wang, Zhichao, Xu, Yichi, Yao, Xiao, Bao, Menghan, Yan, Jun, Song, Haiyun, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185346/
https://www.ncbi.nlm.nih.gov/pubmed/25223702
http://dx.doi.org/10.1038/cr.2014.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185346/
https://www.ncbi.nlm.nih.gov/pubmed/25223702
http://dx.doi.org/10.1038/cr.2014.120

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