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Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates

Neonatal hypoxic ischaemic (HI) injury frequently causes neural impairment in surviving infants. Our knowledge of the underlying molecular mechanisms is still limited. Protein deimination is a post-translational modification caused by Ca(+2)-regulated peptidylarginine deiminases (PADs), a group of f...

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Detalles Bibliográficos
Autores principales: Lange, Sigrun, Rocha-Ferreira, Eridan, Thei, Laura, Mawjee, Priyanka, Bennett, Kate, Thompson, Paul R, Subramanian, Venkataraman, Nicholas, Anthony P, Peebles, Donald, Hristova, Mariya, Raivich, Gennadij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185393/
https://www.ncbi.nlm.nih.gov/pubmed/24762056
http://dx.doi.org/10.1111/jnc.12744