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Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates
Neonatal hypoxic ischaemic (HI) injury frequently causes neural impairment in surviving infants. Our knowledge of the underlying molecular mechanisms is still limited. Protein deimination is a post-translational modification caused by Ca(+2)-regulated peptidylarginine deiminases (PADs), a group of f...
Autores principales: | Lange, Sigrun, Rocha-Ferreira, Eridan, Thei, Laura, Mawjee, Priyanka, Bennett, Kate, Thompson, Paul R, Subramanian, Venkataraman, Nicholas, Anthony P, Peebles, Donald, Hristova, Mariya, Raivich, Gennadij |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185393/ https://www.ncbi.nlm.nih.gov/pubmed/24762056 http://dx.doi.org/10.1111/jnc.12744 |
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