Formal Modelling of Toll like Receptor 4 and JAK/STAT Signalling Pathways: Insight into the Roles of SOCS-1, Interferon-β and Proinflammatory Cytokines in Sepsis

Sepsis is one of the major causes of human morbidity and results in a considerable number of deaths each year. Lipopolysaccharide-induced sepsis has been associated with TLR4 signalling pathway which in collaboration with the JAK/STAT signalling regulate endotoxemia and inflammation. However, during...

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Detalles Bibliográficos
Autores principales: Paracha, Rehan Zafar, Ahmad, Jamil, Ali, Amjad, Hussain, Riaz, Niazi, Umar, Tareen, Samar Hayat Khan, Aslam, Babar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185881/
https://www.ncbi.nlm.nih.gov/pubmed/25255432
http://dx.doi.org/10.1371/journal.pone.0108466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185881/
https://www.ncbi.nlm.nih.gov/pubmed/25255432
http://dx.doi.org/10.1371/journal.pone.0108466

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