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Pentavalent replicon vaccines against botulinum neurotoxins and tetanus toxin using DNA-based Semliki Forest virus replicon vectors

The clostridial neurotoxin (CNT) family includes botulinum neurotoxin (BoNT), serotypes A, B, E, and F of which can cause human botulism, and tetanus neurotoxin (TeNT), which is the causative agent of tetanus. This suggests that the greatest need is for a multivalent or multiagent vaccine that provi...

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Detalles Bibliográficos
Autores principales: Yu, YunZhou, Liu, Si, Ma, Yao, Gong, Zheng-Wei, Wang, Shuang, Sun, Zhi-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186014/
https://www.ncbi.nlm.nih.gov/pubmed/25424795
http://dx.doi.org/10.4161/hv.28937