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Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo

Rotavirus (RV) is a common cause of severe gastroenteritis (GE) in children worldwide. Live oral RV vaccines protect against severe RVGE, but the immune correlates of protection are not yet clearly defined. Inner capsid VP6 protein is a highly conserved, abundant, and immunogenic RV protein, and VP6...

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Detalles Bibliográficos
Autores principales: Lappalainen, Suvi, Pastor, Ana Ruth, Tamminen, Kirsi, López-Guerrero, Vanessa, Esquivel-Guadarrama, Fernando, Palomares, Laura A, Vesikari, Timo, Blazevic, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186038/
https://www.ncbi.nlm.nih.gov/pubmed/25424814
http://dx.doi.org/10.4161/hv.28858