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Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo
Rotavirus (RV) is a common cause of severe gastroenteritis (GE) in children worldwide. Live oral RV vaccines protect against severe RVGE, but the immune correlates of protection are not yet clearly defined. Inner capsid VP6 protein is a highly conserved, abundant, and immunogenic RV protein, and VP6...
Autores principales: | Lappalainen, Suvi, Pastor, Ana Ruth, Tamminen, Kirsi, López-Guerrero, Vanessa, Esquivel-Guadarrama, Fernando, Palomares, Laura A, Vesikari, Timo, Blazevic, Vesna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186038/ https://www.ncbi.nlm.nih.gov/pubmed/25424814 http://dx.doi.org/10.4161/hv.28858 |
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