Nigramide J is a novel potent inverse agonist of the human constitutive androstane receptor

The constitutive androstane receptor (CAR, NR1I3) is very important for drug development and for understanding pharmacokinetic drug–drug interactions. We screened by mammalian one hybrid assay among natural compounds to discover novel ligands of human constitutive androstane receptor (hCAR). hCAR tr...

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Detalles Bibliográficos
Autores principales: Kanno, Yuichiro, Tanuma, Nobuaki, Yatsu, Tomofumi, Li, Wei, Koike, Kazuo, Inouye, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186399/
https://www.ncbi.nlm.nih.gov/pubmed/25505573
http://dx.doi.org/10.1002/prp2.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186399/
https://www.ncbi.nlm.nih.gov/pubmed/25505573
http://dx.doi.org/10.1002/prp2.18

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