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Mapping the sevoflurane-binding sites of calmodulin

General anesthetics, with sevoflurane (SF) being the first choice inhalational anesthetic agent, provide reversible, broad depressor effects on the nervous system yet have a narrow margin of safety. As characterization of low-affinity binding interactions of volatile substances is exceptionally chal...

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Detalles Bibliográficos
Autores principales: Brath, Ulrika, Lau, Kelvin, Van Petegem, Filip, Erdélyi, Máté
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186402/
https://www.ncbi.nlm.nih.gov/pubmed/25505574
http://dx.doi.org/10.1002/prp2.25