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Mapping the sevoflurane-binding sites of calmodulin
General anesthetics, with sevoflurane (SF) being the first choice inhalational anesthetic agent, provide reversible, broad depressor effects on the nervous system yet have a narrow margin of safety. As characterization of low-affinity binding interactions of volatile substances is exceptionally chal...
Autores principales: | Brath, Ulrika, Lau, Kelvin, Van Petegem, Filip, Erdélyi, Máté |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186402/ https://www.ncbi.nlm.nih.gov/pubmed/25505574 http://dx.doi.org/10.1002/prp2.25 |
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