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Regulation of prostaglandin EP(1) and EP(4) receptor signaling by carrier-mediated ligand reuptake

After synthesis and release from cells, prostaglandin E(2) (PGE(2)) undergoes reuptake by the prostaglandin transporter (PGT), followed by cytoplasmic oxidation. Although genetic inactivation of PGT in mice and humans results in distinctive phenotypes, and although experiments in localized environme...

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Detalles Bibliográficos
Autores principales: Chi, Yuling, Suadicani, Sylvia O, Schuster, Victor L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186417/
https://www.ncbi.nlm.nih.gov/pubmed/25505603
http://dx.doi.org/10.1002/prp2.51