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Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome

Cytochrome P450 (CYP) 3A4 is a membrane protein that catalyzes hydroxylation of endogenous and exogenous substrates. Protein–protein interaction is a crucial factor that regulates the function of enzymes. However, protein–protein interactions involving human CYPs have not been fully understood. In t...

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Detalles Bibliográficos
Autores principales: Fujiwara, Ryoichi, Itoh, Tomoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186418/
https://www.ncbi.nlm.nih.gov/pubmed/25505604
http://dx.doi.org/10.1002/prp2.53