Effect of perampanel, a novel AMPA antagonist, on benzodiazepine-resistant status epilepticus in a lithium-pilocarpine rat model

This study assessed the efficacy of diazepam, and the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor antagonists perampanel and GYKI52466 in a lithium-pilocarpine status epilepticus (SE) model. SE was induced in rats using lithium chloride, scopolamine methyl bromide, and...

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Detalles Bibliográficos
Autores principales: Hanada, Takahisa, Ido, Katsutoshi, Kosasa, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186423/
https://www.ncbi.nlm.nih.gov/pubmed/25505607
http://dx.doi.org/10.1002/prp2.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186423/
https://www.ncbi.nlm.nih.gov/pubmed/25505607
http://dx.doi.org/10.1002/prp2.63

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